Large negatively charged organic host molecules as inhibitors of endonuclease enzymes.

نویسندگان

  • Yannick Tauran
  • Christophe Anjard
  • Beomjoon Kim
  • Moez Rhimi
  • Anthony W Coleman
چکیده

Three large negatively charged organic host molecules; β-cyclodextrin sulphate, para-sulphonato-calix[6]arene and para-sulphonato-calix[8]arene have been shown to be effective inhibitors of endonuclease in the low micromolar range, additionally para-sulphonato-calix[8]arene is a partial inhibitor of rhDNase I.

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عنوان ژورنال:
  • Chemical communications

دوره 50 77  شماره 

صفحات  -

تاریخ انتشار 2014